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Multiple Choice

For melioidosis, the recommended duration of oral eradication therapy after IV treatment is typically 3-6 months.

After controlling the acute infection with intravenous antibiotics, melioidosis requires a prolonged oral eradication phase to prevent relapse. Burkholderia pseudomallei can persist inside host cells and in abscesses, so clearing all hidden bacteria takes several weeks to months. For most patients, this eradication period is three to six months, long enough to reduce relapse risk after the IV treatment. Shorter courses are usually inadequate to eliminate lingering bacteria, while much longer durations are reserved for more complicated disease and guided by clinical judgment. Therefore, three to six months is the typical and best-supported duration.

After controlling the acute infection with intravenous antibiotics, melioidosis requires a prolonged oral eradication phase to prevent relapse. Burkholderia pseudomallei can persist inside host cells and in abscesses, so clearing all hidden bacteria takes several weeks to months. For most patients, this eradication period is three to six months, long enough to reduce relapse risk after the IV treatment. Shorter courses are usually inadequate to eliminate lingering bacteria, while much longer durations are reserved for more complicated disease and guided by clinical judgment. Therefore, three to six months is the typical and best-supported duration.